The MSG Migraine Connection

The Truth in Labeling Campaign
3 min readMay 16, 2024

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Despite the glutamate industry’s widely disseminated marketing material, practically every headache clinic in the U.S. lists MSG as a migraine trigger. FDA records even list migraines as the single most common reaction to both MSG and the low-cal sweetener aspartame (both of which contain excitotoxic amino acids.)

In addition, the Truth in Labeling Campaign has received untold numbers of reports over the years from those who were able to prevent the intense suffering of a migraine by eliminating sources of manufactured free glutamate — which include MSG and dozens of other additives.

You would think that recent findings from the University of Utah would put the “MSG doesn’t cause migraines myth” away for good. The study, published in the journal Neuron, found that migraines appear to be triggered by “massive ‘plumes’ of glutamate,” described by the researchers as filling the “area between brain cells” and sparking “tsunami-like waves of activity that spread across the brain in migraine and other nervous system disorders.”

Researcher K.C. Brennan, M.D., who participated in the study, calls glutamate plumes “a completely new mechanism of migraine, and it’s a good bet that they are players in other diseases of the nervous system.”

While glutamate plumes may be “something new under the sun,” if you are a frequent blog-reader of the Truth in Labeling Campaign, the fact that free glutamate is a causative factor in a slew of neurological and non-neurological abnormalities, not just migraines, won’t be a new concept. And the fact that this study doesn’t turn up top-of-the-list for searches on “migraines” is both bad news for the many millions who suffer from what the World Health Organization calls one of the “10 most disabling medical illnesses” one can have, and testimony to the clout of the glutamate industry to keep anything negative about MSG from appearing in major media.

You can read MSG linked to migraines? Chemical used in processed food could trigger brutal headaches at: https://www.studyfinds.org/msg-migraines-processed-food/ And as you do, note that even while describing in detail how devastating these glutamate plumes can be, the article’s author appears to have felt compelled to promote the “no definite link” between MSG and “poor health” concept the Glutes so often manage to get into print.

As always, the Truth in Labeling Campaign has questions.

What would it take to recognize a definite link between MSG and poor health? Would the manufacturer of MSG have to admit that MSG causes reactions such as migraine headache along with brain damage — and that the FDA has been representing glutamate-industry interests since 1968, if not before?

There are seven lines of evidence leading to the conclusion that manufactured free glutamate, no matter where it is found, is excitotoxic. See https://bit.ly/3vkZ6Cl or if you like graphics with your information, https://7lines.org. Take special note of the details of industry’s programs for rigging studies: https://www.truthinlabeling.org/assets/seven_lines/Seven_Lines_Lines3.pdf and: https://www.truthinlabeling.org/assets/seven_lines/Seven_Lines_Line6.pdf.

You might also be interested in details of the role played by the FDA https://www.truthinlabeling.org/assets/industrys_fda_final.pdf.

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The Truth in Labeling Campaign

TLC was incorporated in 1994 as a nonprofit organization dedicated to securing full and clear labeling of all processed food. www.truthinlabeling.org